By topics

SNARE-mediated membrane fusion

  1. D.G. Gamage, K. Melikov, P. Munoz-Tello, T. Wherley, L. Focke, E. Huffman, J. Diao, D.J. Kojetin, V. Prasad, L.V. Chernomordik, D.P. Millay. Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion. (2022).

  2. L. Wang, J. Diao. VAMP8 phosphorylation regulates lysosome dynamics in autophagy. Autophagy Rep. 1, 79 (2022).

  3. Q. Chen, M. Hao, L. Wang, L. Li, Y. Chen, X. Shao, Z. Tian, R.A. Pfuetzner, Q. Zhong, A.T. Brunger, J.-L. Guan, J. Diao. Prefused lysosomes cluster on autophagosomes regulated by VAMP8. Cell Death Dis. 12, 939 (2021).

  4. M. Li, T.-J. Oh, H. Fan, J. Diao, K. Zhang. Syntaxin clustering and optogenetic control for synaptic membrane fusion. J. Mol. Biol. 432, 4773 (2020).

  5. C. Wang, J. Tu, S. Zhang, B. Cai, Z. Liu, S. Hou, Q. Zhong, X. Hu, W. Liu, G. Li, Z. Liu, L. He, J. Diao, Z.-J. Zhu, D. Li, C. Liu. Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly. Nat. Commun. 11, 1531 (2020).

  6. N. Brose, A. Brunger, D. Cafiso, E.R. Chapman, J. Diao, F.M. Hughson, M.B. Jackson, R. Jahn, M. Lindau, C. Ma, J. Rizo, Y.-K. Shin, T.H. Söllner, L. Tamm, T.-Y. Yoon, Y. Zhang. Synaptic vesicle fusion: today and beyond. Nat. Struct. Mol. Biol. 26, 663 (2019).

  7. Z. Tian, J. Gong, M. Crowe, M. Lei, D. Li, B. Ji, J. Diao. Biochemical studies of membrane fusion at the single-vesicle level. Prog. Lipid Res. 73, 92 (2019).

  8. Y. Hu, Z. Tian, J. Diao. Single-molecule fluorescence measurement of SNARE-mediated vesicle fusion. Methods Mol. Biol. 1860, 335 (2019).

  9. E. Leikina, D.G. Gamage, V. Prasad, J. Goikberg, M. Crowe, J. Diao, M.M. Kozlov, L.V. Chernomordik, D.P. Millay. Myomaker and Myomerger work independently to control distinct steps of membrane remodeling during myoblast fusion. Dev. Cell 46, 767 (2018).

  10. Y. Hu, Y. Lai, Y. Wang, M. Zhao, Y. Zhang, M. Crowe, Z. Tian, J. Long, J. Diao. SNARE-reconstituted liposomes as controllable zeptoliter nanoreactors for macromolecules. Adv. Biosyst. 1, 1600018 (2017).

  11. J. Diao, L. Li, Y. Lai, Q. Zhong. In vitro reconstitution of autophagosome-lysosome fusion. Methods Enzymol. 587, 365 (2017).

  12. Y. Wang, L. Li, C. Hou, Y. Lai, J. Long, J. Liu, Q. Zhong, J. Diao. SNARE-mediated membrane fusion in autophagy. Semin. Cell Dev. Biol. 60, 97 (2016).

  13. J. Gong, Y. Lai, X. Li, M. Wang, J. Leitz, Y. Hu, Y. Zhang, U.B. Choi, D. Cipriano, R.A. Pfuetzner, T.C. Südhof, X. Yang, A.T. Brunger, J. Diao. C-terminaldomain of mammalian complexin-1 localizes to highly curved membranes. Proc. Natl. Acad. Sci. USA 113, E7590 (2016).

  14. Z. Tian, Y. Hu, J. Long, J. Liu, J. Diao. Single-molecule biophysical studies of neurotransmitter release. Prog. Biochem. Biophys. 43, 946 (2016). [in Chinese]

  15. Y. Lai, U.B. Choi, Y. Zhang, R.A. Pfuetzner, A.L. Wang, J. Diao, A.T. Brunger. N-terminaldomain of complexin independently activates calcium-triggered fusion. Proc. Natl. Acad. Sci. USA 113, E4698 (2016).

  16. S. Malmersjö, S. Di Palma, J. Diao, Y. Lai, R.A. Pfuetzner, A.L. Wang, M.A. McMahon, A. Hayer, M. Porteus, B. Bodenmiller, A.T. Brunger, T. Meyer. Phosphorylation of residues inside the SNARE complex terminates secretory vesicle fusion. EMBO J. 35, 1810 (2016).

  17. Q. Zhou, Y. Lai, T. Bacaj, M. Zhao, A.Y. Lyubimov, M. Uervirojnangkoorn, O.B. Zeldin, A.S. Brewster, N.K. Sauter, A.E. Cohen, S.M. Soltis, R. Alonso-Mori, M. Chollet, H.T. Lemke, R.A. Pfuetzner, U.B. Choi, W.I. Weis, J. Diao, T.C. Südhof, A.T. Brunger. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature 525, 62 (2015).

  18. J. Diao, R. Liu, Y. Rong, M. Zhao, J. Zhang, Y. Lai, Q. Zhou, L.M. Wilz, J. Li, S. Vivona, R.A. Pfuetzner, A.T. Brunger, Q. Zhong. ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature 520, 563 (2015).

  19. Y. Lai, L. Zhao, B. Bu, X. Lou, D. Li, B. Ji, J. Liu, J. Diao, Y.-K. Shin. Lipid molecules influence early stages of yeast SNARE mediated membrane fusion. Phy. Biol. 12, 025003 (2015).

  20. Y. Zhang, J. Diao, K.N. Colbert, Y. Lai, R.A. Pfuetzner, M.S. Padolina, S. Vivona, S. Ressl, D.J. Cipriano, U.B. Choi, N. Shah, W.I. Weis, A.T. Brunger. Munc18a does not alter fusion rates mediated by neuronal SNAREs, synaptotagmin, and complexin. J. Biol. Chem. 290, 10518 (2015).

  21. Y. Lai, X. Lou, J. Diao, Y.-K. Shin. Molecular origins of multiple synaptotagmin 1 functions in Ca2+-triggered neuroexocytosis. Sci. Rep. 5, 9267 (2015).

  22. A.T. Brunger, D.J. Cipriano, J. Diao. Towards reconstitution of membrane fusion Mediated by synaptic proteins. Crit. Rev. Biochem. Mol. Biol. 50, 231 (2015).

  23. Y. Lai, J. Diao, D.J. Cipriano, Y. Zhang, R.A. Pfuetzner, M.S. Padolina, A.T. Brunger. Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms. Elife 3, e03756 (2014).

  24. J. Diao, M. Zhao, Y. Zhang, M. Kyoung, A.T. Brunger. Studying protein-reconstituted proteoliposome fusion with content indicators in vitro. Bioessays 35, 658 (2013).

  25. J. Diao, D.J. Cipriano, M. Zhao, Y. Zhang, S. Shah, M.S. Padolina, R.A. Pfuetzner, A.T. Brunger. Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions. J. Am. Chem. Soc. 135, 15274 (2013).

  26. Y. Lai, J. Diao, Y. Liu, Y. Ishitsuka, Z. Su, K. Schulten, T. Ha, Y.-K. Shin. Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1. Proc. Natl. Acad. Sci. USA 110, 1333 (2013).

  27. M. Kyoung, Y. Zhang, J. Diao, S. Chu, A.T. Brunger. Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system. Nat. Protoc. 8, 1 (2013).

  28. J. Diao, P. Grob, D.J. Cipriano, M. Kyoung, Y. Zhang, S. Shah, A. Nguyen, M. Padolina, A. Srivastava, M. Vrljic, A. Shah, E. Nogales, S. Chu, A.T. Brunger. Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. Elife 1, e00109 (2012).

  29. J. Diao, Y. Ishitsuka, H.-K. Lee, C. Joo, Z. Su, S. Syed, Y.-K. Shin, T.-Y. Yoon, T. Ha. A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins. Nat. Protoc. 7, 921 (2012).

  30. J. Diao, Y. Ishitsuka, W.-R. Bae. Single-molecule FRET study of SNARE-mediated membrane fusion. Biosci. Rep. 31, 457 (2011).

  31. M. Kyoung, A. Srivastava, Y. Zhang, J. Diao, M. Vrljic, P. Grob, E. Nogales, S. Chu, A.T. Brunger. In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release. Proc. Natl. Acad. Sci. USA 108, E304 (2011).

  32. J. Diao, Z. Su, Y. Ishitsuka, B. Lu, K.S. Lee, Y. Lai, Y.-K. Shin, T. Ha. A single vesicle content-mixing assay for SNARE-mediated membrane fusion. Nat. Commun. 1, 54 (2010).

  33. J. Diao, Z. Su, X. Lu, T.-Y. Yoon, Y.-K. Shin, T. Ha. Single vesicle fusion assay reveals Munc18-1 binding to the SNARE core is sufficient for stimulating membrane fusion. ACS Chem. Neurosci. 1, 168 (2010).

  34. T.-Y. Yoon, X. Lu, J. Diao, S.-M. Lee, T. Ha, Y.-K. Shin. Complexin and Ca2+ stimulate SNARE-mediated membrane fusion. Nat. Struct. Mol. Biol. 15, 707 (2008).


  1. K. Wu, W. Sun, D. Li, J. Diao, P. Xiu. Inhibition of amyloid nucleation by steric hindrance. (2022).

  2. C.M. Aryal, O. Tyoe, J. Diao. Lipid species dependent vesicles clustering caused by alpha-synuclein as revealed by single-vesicle imaging with total internal reflection fluorescence microscopy. Biophys. Rep. 7, 437 (2021).

  3. J. Liu, B. Bu, M. Crowe, D. Li, J. Diao, B. Ji. Membrane packing defects in synaptic vesicles recruit complexin and synuclein. Phys. Chem. Chem. Phys. 23, 2117 (2021).

  4. K. Wu, D. Li, P. Xiu, B. Ji, J. Diao. O-GlcNAcylation inhibits the oligomerization of alpha-synuclein by declining intermolecular hydrogen bonds through a steric effect. Phys. Biol. 18, 016002 (2020).

  5. B. Cai, J. Liu, Y. Zhao, X. Xu, B. Bu, D. Li, L. Zhang, W. Dong, B. Ji, J. Diao. Single-vesicle imaging quantifies calcium’s regulation of nanoscale vesicle clustering mediated by α-synuclein. Microsyst. Nanoeng. 6, 38 (2020).

  6. D.-F. Ma, C.-H. Xu, W.-Q. Hou, C.-Y. Zhao, J.-B. Ma, X.-Y. Huang, Q. Jia, L. Ma, J. Diao, C. Liu, M. Li, Y. Lu. Detecting single molecule dynamics on lipid membranes with quenchers-in-a-liposome FRET. Angew. Chem. Int. Ed. 58, 5577 (2019).

  7. X. Li, X. Tong, W. Lu, D. Yu, J. Diao, Q. Zhao. Label-free detection of early oligomerization of α-synuclein and its mutants A30P/E46K through solid-state nanopores. Nanoscale 11, 6480 (2019).

  8. B. Cai, L. Yu, S.R. Sharum, K. Zhang, J. Diao. Single-vesicle measurement of protein-induced membrane tethering. Colloids Surf. B-Biointerfaces 177, 267 (2019).

  9. B. Bu, X. Tong, D. Li, Y. Hu, W. He, C. Zhao, R. Hu, X. Li, Y. Shao, C. Liu, Q. Zhao, B. Ji, J. Diao. N-terminal acetylation preserves α-synuclein from oligomerization by blocking intermolecular hydrogen bonds. ACS Chem. Neurosci. 8, 2145 (2017).

  10. X. Li, R. Hu, J. Li, X. Tong, J.J. Diao, D. Yu, Q. Zhao. Non-sticky translocation of bio-molecules through Tween 20-coated solid-state nanopores in a wide pH range. Appl. Phys. Lett. 109, 143105 (2016).

  11. C. Wang, C. Zhao, D. Li, Z. Tian, Y. Lai, J. Diao, C. Liu. Versatile structures of α-synuclein. Front. Mol. Neurosci. 9, 48 (2016).

  12. R. Hu, J. Diao, J. Li, Z. Tang, X. Li, J. Leitz, J. Long, J. Liu, D. Yu, Q. Zhao. Intrinsic and membrane-facilitated oligomerization of α-synuclein revealed by a label-free detection through solid-state nanopores. Sci. Rep. 6, 20776 (2016).

  13. Y. Lai, S. Kim, J. Varkey, X. Lou, J.-K. Song, J. Diao, R. Langen, Y.-K. Shin. Non-aggregated α-synuclein influences SNARE-dependent vesicle docking via membrane binding. Biochemistry 53, 3889 (2014).

  14. J. Burré, S. Vivona, J. Diao, M. Sharma, A.T. Brunger, T.C. Südhof. Properties of native brain α-synuclein. Nature 498, E4 (2013).

  15. J. Diao, J. Burré, S. Vivona, D.J. Cipriano, M. Sharma, M. Kyoung, T.C. Südhof, A.T. Brunger. Native α-synuclein induces clustering of synaptic vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2. Elife 2, e00592 (2013).

Imaging and controlling subcellular dynamics

  1. K. Qiu, A. Yadav, Z. Tian, Z. Guo, D. Shi, C.K. Nandi, J. Diao. Ultra-long-term super-resolution tracking of lysosomes in brain organoids by near-infrared noble metal nanoclusters. (2022).

  2. H. Fang, L. Hu, Q. Chen, S. Geng, C. Wang, M. Hao, Z. Tian, H. Chen, L. Liu, J.-L. Guan, Y. Chen, L. Dong, Z. Guo, W. He, J. Diao. An ER-targeted “reserve-release” fluorogen for topological quantification of reticulophagy. (2022).

  3. K. Qiu, W. Zou, H. Fang, M. Hao, K. Mehta, Z. Tian, J.-L. Guan, K. Zhang, T. Huang, J. Diao. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nat. Commun. 13, (2022).

  4. G. Fang, H. Chen, X. Shao, H. Wang, D. Zhan, R. Wang, P. Meng, H. Fang, F. Liu, P. Ling, Z. Wu, J. Diao, Q. Yao, Q. Chen. Single image capture of bioactive ion crosstalk within inter-organelle membrane contacts at nanometer resolution. Small Methods 6, 2200321 (2022).

  5. L. Wang, R. Chen, G. Han, X. Liu, T. Huang, J. Diao, Y. Sun. Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe. Exploration 2, 0210215 (2022).

  6. K. Qiu, R. Seino, G. Han, M. Ishiyama, Y. Ueno, Z. Tian, Y. Sun, J. Diao. De novo design of a membrane-anchored probe for multi-dimensional quantification of endocytic dynamics. Adv. Healthc. Mater. 11, 2102185 (2022).

  7. K.-N. Wang, X. Shao, Z. Tian, L.-Y. Liu, C. Zhang, C.-P. Tan, J. Zhang, P. Ling, F. Liu, Q. Chen, J. Diao, Z.-W. Mao. A continuously add-on probe reveals a nonlinear enlargement of mitochondria in light-activated oncosis. Adv. Sci. 8, 2004566 (2021).

  8. W. Zou, Q. Chen, J. Slone, L. Yang, X. Lou, J. Diao, T. Huang. Nanoscopic quantification of sub-mitochondrial morphology, mitophagy and mitochondrial dynamics in living cells derived from patients with mitochondrial diseases. J. Nanobiotechnol. 19, 136 (2021).

  9. H. Fang, S. Geng, M. Hao, Q. Chen, M. Liu, C. Liu, Z. Tian, C. Wang, T. Takebe, J.-L. Guan, Y. Chen, Z. Guo, W. He, J. Diao. Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells. Nat. Commun. 12, 109 (2021).

  10. Q. Chen, H. Fang, X. Shao, Z. Tian, S. Geng, Y. Zhang, H. Fan, P. Xiang, J. Zhang, X. Tian, K. Zhang, W. He, Z. Guo, J. Diao. A dual-labeling molecular probe to track functional mitochondria-lysosome interactions in live cells. Nat. Commun. 11, 6290 (2020).

  11. L.-Y. Liu, H. Fang, Q. Chen, M. H.-Y. Chan, M. Ng, K.-N. Wang, W. Liu, Z. Tian, J. Diao, Z.-W. Mao, V. W.-W. Yam. Multiple-color platinum complex with super-large Stokes shift for super-resolution imaging of autolysosome escape. Angew. Chem. Int. Ed. 59, 19229 (2020).

  12. K. Qiu, Y. Du, J. Liu, J.-L. Guan, H. Chao, J. Diao. Super-resolution observation of lysosomal dynamics with fluorescent gold nanoparticles. Theranostics 10, 6072 (2020).

  13. X. Shao, Q. Chen, L. Hu, Z. Tian, L. Liu, F. Liu, F. Wang, P. Ling, Z.-W. Mao, J. Diao. Super-resolution quantification of nanoscale damage to mitochondria in live cells. Nano Res. 13, 2149 (2020).

  14. Q. Chen, X. Shao, M. Hao, R. Guan, Z. Tian, M. Li, C. Wang, L. Ji, H. Chao, J.-L. Guan, J. Diao. Quantitative analysis of interactive behavior of mitochondria and lysosomes using structured illumination microscopy. Biomaterials 250, 120059 (2020).

  15. H. Fang, S. Yao, Q. Chen, C. Liu, Y. Cai, S. Geng, Y. Bai, Z. Tian, A.L. Zacharias, T. Takebe, Y. Chen, Z. Guo, W. He, J. Diao. De novo-designed near-infrared nanoaggregates for super-resolution monitoring of lysosomes in cells, in whole organoids, and in vivo. ACS Nano 13, 14426 (2019).

  16. Q. Chen, X. Shao, Z. Tian, Y. Chen, P. Mondal, F. Liu, F. Wang, P. Ling, W. He, K. Zhang, Z. Guo, J. Diao. Nanoscale monitoring of mitochondria and lysosome interactions for drug screening and discovery. Nano Res. 12, 1009 (2019).

  17. J. Khamo, V. Krishnamurthy, Q. Chen, J. Diao, K. Zhang. Optogenetic delineation of receptor tyrosine kinase subcircuits during PC12 cell differentiation. Cell Chem. Biol. 26, 400 (2019).

  18. Q. Chen, C. Jin, X. Shao, R. Guan, Z. Tian, C. Wang, F. Liu, P. Ling, J. Guan, L. Ji, F. Wang, H. Chao, J. Diao. Super-resolution tracking of mitochondrial dynamics with an Iridium(III) luminophore. Small 14, 1802166 (2018).

  19. K. Qiu, L. Ke, X. Zhang, Y. Liu, T.W. Rees, L. Ji, J. Diao, H. Chao. Tracking mitochondrial pH fluctuation during cell apoptosis with two-photon phosphorescent Iridium(III) complexes. Chem. Commun. 54, 2421 (2018).

  20. H. Huang, L. Yang, P. Zhang, K. Qiu, J. Huang, Y. Chen, J. Diao, J. Liu, L. Ji, J. Long, H. Chao. Real-time tracking mitochondrial dynamic remodeling with two-photon phosphorescent Iridium (III) complexes. Biomaterials 83, 321 (2016).

Single-molecule FRET

  1. Y. Wang, X. Hu, J. Long, J. Diao. Epigenetic optical sensing of 5-hydroxymethylcytosine at the single-molecule level. Sens. Actuator B-Chem 358, 131500 (2022).

  2. Y. Tao, J. Xie, Q. Zhong, Y. Wang, S. Zhang, F. Luo, F. Wen, J. Xie, J. Zhao, X. Sun, H. Long, J. Ma, Q. Zhang, J. Long, X. Fang, Y. Lu, D. Li, M. Li, J. Zhu, B. Sun, G. Li, J. Diao, C. Liu. A novel partially-open state of SHP2 points to a “multiple gear” regulation mechanism. J. Biol. Chem. 296, 100538 (2021).

  3. Y. Du, Y. Lai, J. Liu, J. Diao. Epigenetic quantification of DNA 5-hydroxymethylcytosine using DNA hybridization-based single-molecule immunofluorescent imaging. Small Methods 5, 2100061 (2021).

  4. E. Lerner et al. FRET-Based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. Elife 10, e60416 (2021).

  5. Y. Du, Y. Wang, X. Hu, J. Liu, J. Diao. Single-molecule quantification of 5-methylcytosine and 5-hydroxymethyicytosine in cancer genome. View 1, e9 (2020).

  6. X. Feng, S.-J. Hsu, A. Bhattacharjee, Y. Wang, J. Diao, C.M. Price. CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells. Nat. Commun. 9, 2827 (2018).

  7. A. Bhattacharjee, Y. Wang, J. Diao, C.M. Price. Dynamic DNA binding, junction recognition and G4 melting activity underlie the telomeric and genome-wide roles of human CST. Nucleic Acids Res. 45, 12311 (2017).

  8. Y. Qing, Z. Tian, Y. Bi, Y. Wang, J. Long, C.-X. Song, J. Diao. Quantitation and mapping of the epigenetic marker 5-hydroxymethylcytosine. Bioessays 39, 1700010 (2017).

  9. C.-X. Song, J. Diao, A.T. Brunger, S.R. Quake. Simultaneous single-molecule epigenetic imaging of DNA methylation andhydroxymethylation. Proc. Natl. Acad. Sci. USA 113, 4338 (2016).

Membrane biophysics

  1. K. Qiu, W. Zou, Z. Fang, S. Bell, X. Zhang, Z. Tian, X. Xu, B. Ji, D. Li, T. Huang, J. Diao. 2D MoS2 and BN nanosheets damage mitochondria through membrane penetration. (2022).

  2. Z. Wang, H. Fan, X. Hu, J. Khamo, J. Diao, K. Zhang, T.V. Pogorelov. Coaction of electrostatic and hydrophobic interactions: dynamic structural constraints on disordered TrkA juxtamembrane domain. J. Phys. Chem. B 123, 10709 (2019).

  3. Q. Wang, X. Zhai, M. Crowe, L. Guo, Y. Li, D. Li, L. Zhang, J. Diao, B. Ji. Heterogeneous oxidization of graphene nanosheets damages membrane. Sci. China-Phys. Mech. Astron. 62, 064611 (2019).

  4. B. Bu, M. Crowe, J. Diao, B. Ji, D. Li. Cholesterol suppresses membrane leakage by decreasing water penetrability. Soft Matter 14, 5277 (2018).

  5. M. Crowe, Y. Lai, Y. Wang, J. Lu, M. Zhao, Z. Tian, J. Long, P. Zhang, J. Diao. A proteoliposome method for assessing nanotoxicity on synaptic fusion and membrane integrity. Small Methods 1, 1700207, (2017).

  6. B. Bu, D. Li, J. Diao, B. Ji. Mechanics of water pore formation in lipid membrane under electric field. Acta Mech. Sin. 33, 234 (2017).

  7. J. Diao, T.-Y. Yoon, Z. Su, Y.-K. Shin, T. Ha. C2AB: a molecular glue for lipid vesicles with negatively charged surface. Langmuir 25, 7177 (2009).


  1. J. Yan, Y. Wang, X. Li, D. Guo, Z. Zhao, G. Bai, J. Li, N. Huang, J. Diao, Y. Li, W. He, W. Liu, K. Tao. A bionic nano band-aid constructed by a three-stage self-assembly of peptides for rapid liver hemostasis. Nano Lett. 21, 7166 (2021).

  2. X. Zheng, J. Yan, W. You, F. Li, J. Diao, W. He, Y. Yao. De novo nano-erythrocyte structurally braced by biomimetic Au(I)-peptide skeleton for MDM2/MDMX predation towards augmented pulmonary adenocarcinoma immunotherapy. Small 17, 2100394 (2021).

  3. J. Sun, K. Du, J. Diao, X. Cai, F. Feng, S. Wang. GSH and H2O2 co-activatable mitochondria-targeted photodynamic therapy under normoxia and hypoxia. Angew. Chem. Int. Ed. 59, 12122 (2020).

  4. X. Jiang, C. Hu, K. Ferchen, J. Nie, X. Cui, C.-H. Chen, L. Cheng, Z. Zuo, W. Seibel, C. He, Y. Tang, J.R. Skibbe, M. Wunderlich, W.C. Reinhold, L. Dong, C. Shen, S. Arnovitz, B. Ulrich, J. Lu, H. Weng, R. Su, H. Huang, Y. Wang, C. Li, X. Qin, J. Mulloy, Y. Zheng, J. Diao, J. Jin, C. Li, P.P. Liu, C. He, Y. Chen, J. Chen. Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia. Nat. Commun. 8, 2099 (2017).

  5. C.-X. Song, S. Yin, L. Ma, A. Wheeler, Y. Chen, Y. Zhang, B. Liu, J. Xiong, W. Zhang, J. Hu, Z. Zhou, B. Dong, Z. Tian, S.S. Jeffrey, M.-S. Chua, S. So, W. Li, Y. Wei, J. Diao, D. Xie, S.R. Quake. 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages. Cell Res. 27, 1231 (2017).


  1. Z. Tian, M. Crowe, L. Shao, P. Zhang, L. Zhang, Q. Zhao, J. Diao. Interface colloidal deposition of nanoparticle wire structures. Part. Part. Syst. Charact. 35, 1800098 (2018).

  2. M. Crowe, Z. Tian, P. Zhang, J.J. Diao. Pristine graphene modulation of vertical colloidal deposition for gold nanoparticle wires. Colloids Surf. A-Physicochem. Eng. Asp. 544, 159 (2018).

  3. S.C. Shen, W. Liu, J.J. Diao. Nanoparticle wire structures for biophysical detections. Chin. Phys. B 24, 127308 (2015).

  4. L. Shao, J.J. Diao, Z. Tang, S. Liu, S.C. Shen, X. Rui, J. Liu, D. Yu, Q. Zhao. Gold nanoparticle wires for sensing DNA and DNA/protein interactions. Nanoscale 6, 4089 (2014).

  5. M. Xia, X. Rui, J.J. Diao. Heat and electronic coupling transport in strained graphene nanoribbons. Adv. Sci. Lett. 4, 3658 (2011).

  6. J.J. Diao, S.C. Shen. Charge transfer directed growth and morphology regulation of silver nanoparticles. J. Nanosci. Nanotech. 11, 4158 (2011).

  7. J.J. Diao, Q. Cao. Gold nanoparticle wire and integrated wire array for electronic detection of chemical and biological molecules. AIP Adv. 1, 012115 (2011).

  8. J.J. Diao, M. Xia. A particle transport study of vertical evaporation-driven colloidal deposition by the coffee-ring theory. Colloids Surf. A-Physicochem. Eng. Asp. 338, 167 (2009).

  9. Y. Chen, G. Luo, J.J. Diao, O. Chornoguz, M. Reeves, A. Vertes. Laser desorption/ionization from nanostructured surfaces: nanowires, nanoparticle films and silicon microcolumn arrays. J. Phys. Conf. Ser. 59, 548 (2007). [Eighth International Conference on Laser Ablation (COLA'05), Banff, Canada 2005]

  10. J.J. Diao, H. Chen. Near infrared surface plasmon resonance of gold tabular nanostructures in the HAuCl4-Na2S reaction. J. Chem. Phys. 124, 116103 (2006).

  11. J.J. Diao, J. Sun, J.B. Hutchison, M.E. Reeves. Self assembled nanoparticle wires by discontinuous vertical colloidal deposition. Appl. Phys. Lett. 87, 103113 (2005).

  12. J.J. Diao, J.B. Hutchison, G. Luo, M.E. Reeves. Theoretical analysis of vertical colloidal deposition. J. Chem. Phys. 122, 184710 (2005).

  13. J.J. Diao, S. Huang, M.E. Reeves. Cavity resonators of metal-coated dielectric nanorods. J. Chem. Phys. 122, 146101 (2005).

  14. J.J. Diao, D. Hua, J.Q. Lin, H.H. Teng, D.C. Chen. Nanoparticle delivery by controlled bacteria. J. Nanosci. Nanotech. 5, 1749 (2005).

  15. J.J. Diao, G.D. Chen, F.S. Qiu, G.J. Yan. Improved liquid-solid-gas interface deposition for nanoparticle thin film. Chin. Phys. 13, 1927 (2004).

  16. J.J. Diao, F.S. Qiu, G.D. Chen, M.E. Reeves. Surface vertical deposition for gold nanoparticle film. J. Phys. D-Appl. Phys. 36, L25 (2003).

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